The reigning champions, who have a league-high 54 goals this season, will go for more and stick to their guns against equally-potent Liverpool. There is no doubting the talents of both Aguero and van Dijk, so seeing them come up against each other should be a great spectacle.
"We play the way that the game tells us to play", he added.
The Dutch global has already played a key role behind Liverpool's defensive solidity so far this campaign and his physical dominance coupled with his imposing presence in the backline can be intimidating for any attacker.
The Merseyside outfit have won their last seven Premier League games to help the Reds to establish a substantial lead at the top of the table.
It is the story of the seasons in 2002, 2009 and 2014 where having played their way into a strong position, the emotional intensity, pressure and general nervousness got the better of the club.
"Mistakes are part of the game".
"Hopefully the game after that [City] he will be available again".
On Thursday, he will go toe-to-toe with the man who will no doubt be vying for his place in the Brazil national side in Fabinho.
Where Liverpool and Manchester City's prestige would really show is in Spain.
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Asked if the City defeat laid bare the size of Saints' survival fight, Hasenhuttl replied: "I knew it from the beginning, I knew exactly what a brutal schedule was waiting for us, and to prepare a new team, to know the new players, what they can do for you".
It will then fall on his shoulders to restrict the influence that his fellow Brazilian has on the game.
'But we are only in January and there are still plenty of Premier League games ahead of us.
There's a degree of history to this one.
The first team of the list will obviously be the champions Manchester City.
However, that's easier said than done.
But if Salah spots a chink in the City armour, he will exploit it and continue to do so for the duration and cause devastating problems. Any game you can play like that but obviously every game is different and we need to wait and see how the game is going to be.