It could have been tricky for Madrid.
But English champions Manchester City struggled, with Pep Guardiola watching from the stands after a touchline ban, and were beaten 2-1 by French side Lyon at the Etihad Stadium after an error-strewn display.
"Now UEFA should come out and say, 'gentlemen, we were wrong.' You can't go back on it because Ronaldo has already been sent off and the game is over, but a ban would be absurd".
Former Juve boss Lippi is among those now calling for action, telling Tuttosport of a freakish incident involving one of the finest players on the planet: "The red for Ronaldo was because a person had a hallucination".
Valencia fans celebrated Ronaldo's dismissal at the Estadio Mestalla like a goal had been scored but, in truth, their team missed a golden chance to gain a foothold in Group H.
His decision to celebrate by removing his shirt to flex his muscles proved costly as he was booked and just two minutes later saw a second yellow card for diving in the referee's eyes in an attempt to win a penalty.
Arrest made in 'unprovoked' fatal stabbing of DC jogger
Newsham said there was no robbery and no apparent confrontation before the attack, which he said happened "very quickly". He described the stabbing as an "unprovoked attack ", adding that investigators had not determined a motive.
First, midfielder Daniel Parejo missed a high ball and kicked Joao Cancelo before Murillo took a risk by bundling down Bonucci.
Ronaldo must to wait until next Thursday (Sept 27) to find out if he will be suspended for his return to Old Trafford.
Jose Mourinho's men were inspired by Paul Pogba on the artificial pitch, as the French World Cup victor drilled home a brilliant opener before converting a penalty on the stroke of half-time, and setting up Anthony Martial for the third.
But the French champions pulled one back before the interval through Thomas Meunier - the goal allowed to stand despite Edinson Cavani being offside in the build-up.
"Making my Champions League debut was a unique feeling", the former Liverpool star told the press.
Then 19, a move from Benfica to Bayern Munich seemed to happen too soon and he was sent to Premier League struggler Swansea on loan.
Also in Group E, Ajax marked its return after a four-year absence to join Madrid as the only home teams winning Wednesday, also by 3-0.