Israeli forces, on Friday, shot and killed three Palestinians, including a child, and injured more than 500 others as they descended on the continuing protests at the eastern border of the Gaza Strip, according to the Ministry of Health.
At the same time, Israel has faced fierce criticism over its use of lethal force against Palestinian protesters on the Gaza Strip border with the Jewish state. Others threw stones or flew kites with burning rags attached, aiming to send them over the border and set Israeli fields on fire.
At least 413 Palestinians were wounded, including 80 by live fire, Gaza health officials said.
The latest confrontations came after weeks of Palestinian protests, known as the Great March of Return, near the fence, during which more than 120 Palestinians - including 21-year-old medic Razan Al-Najjar - were killed by Israeli fire.
Israel's deadly tactics in confronting the protests have drawn worldwide condemnation.
Two million Palestinians have sunk into poverty as Israel and Egypt, citing security needs, clamped down on Gaza's borders.
Israel has accused Hamas, which controls Gaza, of orchestrating the protests. Israel claimed Hamas had intentionally provoked the violence, a charge Hamas denied.
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The UN General Assembly will hold an emergency meeting next Wednesday at 3 p.m.to vote on an Arab-backed resolution on Gaza, the body's President Miroslav Lajcak announced Friday.
"What happened today adds to our argument and to the urgency of providing global protection" for Palestinian civilians, he said.
The IDF Spokesperson Unit said, "IDF troops are reinforced along the Gaza Strip security fence in order to protect security infrastructure and defend Israeli civilians in the communities surrounding the Gaza Strip from the attempted terror attacks led by the Hamas terror organization". His family said he was taking part in a protest in Rafah, in southern Gaza, when he was shot.
Friday's march also coincided with the annual "Jerusalem Day", instituted by Iran to protest against Israeli rule of the holy city.
"There is no such state called Israel that could have a capital called Jerusalem", Hamas spokesman Fawzi Barhoum said in Gaza. They pledged to continue raising voice for rights of oppressed Palestinians and rejecting nefarious designs of Israel and USA against people in various parts of the world including Palestine.
Israel has hosted the Eurovision contest twice before in Jerusalem, a city that most countries do not recognize as Israel's capital. There have been no Israeli casualties.
"We are not asking for the moon", said Amer Abu Khalaf, a 20-year-old business administration student who took part in Friday's protest. The marchers have also pressed demands for a "right of return" for the descendants of Palestinian refugees to ancestral homes in what is now Israel.